Impact of metabolic syndrome on oncologic outcome after radical gastrectomy for gastric cancer - 17/06/14
, Hyunsoo Chung a, Jun Chul Park a, Sung Kwan Shin a, Sang Kil Lee a, Woo Jin Hyung b, Yong Chan Lee a, Sung Hoon Noh bBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
| pages | 7 |
| Iconographies | 3 |
| Vidéos | 0 |
| Autres | 0 |
Summary |
Background |
Few studies have reported the relationship between MS and the prognosis of gastric cancer.
Methods |
Data were collected from 505 patients who underwent radical gastrectomy for gastric cancer between January 2006 and December 2007. After exclusion, remaining 204 patients were divided into two groups based on the presence of MS.
Results |
No significant differences were observed in tumor stage and grade between the MS (n=60) and non-MS (n=144) groups. The median follow-up periods were 53.2±23.5 and 54.7±22.1 months in for the MS and non-MS groups, respectively (P=0.677). Seventeen (28.3%) and 21 (14.6%) patients showed tumor recurrence in the MS and non-MS groups, respectively (P=0.022). In addition, disease-free survival of patients in the MS group was less than in non-MS group (P=0.036). The Cox regression hazard model demonstrated that advanced tumor stage (stage III or IV, HR=17.8, 95% CI=5.3 to 59.4) and presence of MS (HR=2.8, 95% CI=1.3 to 5.8) were independent risk factors for recurrence.
Conclusion |
MS may be an important prognostic factor for gastric cancer. Control of MS could improve the therapeutic efficacy of gastric cancer.
Le texte complet de cet article est disponible en PDF.Plan
Vol 38 - N° 3
P. 372-378 - juin 2014 Retour au numéro
Article précédent
- Associations of a TLR4 single-nucleotide polymorphism with H. pylori associated gastric diseases in iranian patients
- Nader Bagheri, Fatemeh Azadegan-Dehkordi, Hosein Sanei, Afshin Taghikhani, Ghorbanali Rahimian, Loghman Salimzadeh, Morteza Hashemzadeh-Chaleshtori, Mahmoud Rafieian-kopaei, Maryam Shirzad, Hedayatollah Shirzad
- Glutathione S-transferase gene polymorphisms in celiac disease and their correlation with genomic instability phenotype
- Ariela F. Fundia, Natalia Weich, Adriana Crivelli, Graciela La Motta, Irene B. Larripa, Irma Slavutsky
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’achat d’article à l’unité est indisponible à l’heure actuelle.
Déjà abonné à cette revue ?