Patients with psoriasis are increasingly turning to the use of alternative and complementary medicine to manage their psoriasis. Patients often inquire about what dietary supplements may be beneficial, including the use of oral vitamin D, vitamin B12, selenium, and omega-3 fatty acids in fish oils. In this review we examine the extent to which each of these common nutritional interventions has been studied for the treatment of psoriasis. We weighed evidence from both controlled and uncontrolled prospective trials. The evidence of benefit was highest for fish oils. For other supplements, there is need for additional large, randomized clinical trials to establish evidence of efficacy.Le texte complet de cet article est disponible en PDF.
Key words : diet, fish oil, nutrition, omega-3, oral vitamin D, psoriasis, selenium, vitamin B12, 1,25-dihydroxycholecalciferol, 1,25-dihydroxyvitamin D3, 1,25-(OH)2D3
Abbreviations used : DHA, EPA, PASI, UV
| Dr Millsop and Ms Bhatia contributed equally to this work.
| Dr Liao is supported in part by grants from the National Institutes of Health (R01AR065174, K08AR057763).
| Disclosure: Dr Koo is a speaker for AbbVie and Leo. Dr Koo conducts research for Amgen, Janssen, Novartis, Photomedex, Galderma, Pfizer, and Merck. Dr Koo has no stocks, employment, or board memberships with any pharmaceutical company. None of the grants were directly related to this study. Dr Millsop, Ms Bhatia, Ms Debbaneh, and Dr Liao have no conflicts of interest to declare.