The utility of re-excising mildly and moderately dysplastic nevi: A retrospective analysis - 15/11/14
Abstract |
Background |
The management of dysplastic nevi (DN) is a highly debated and controversial topic within the dermatology community. Clinicians agree that margin-positive severely DN should be removed with a surgical margin, however, there is disagreement surrounding the appropriate management of margin-positive mildly and moderately DN.
Objective |
We sought to evaluate the utility of re-excising margin-positive mildly and moderately DN.
Methods |
A retrospective chart review was conducted on all adult patients given the diagnosis of a biopsy-proven DN from 2010 through 2011. The primary outcomes were defined as the presence of melanocytic residuum in re-excisional specimens and a clinically significant change in diagnosis.
Results |
A total of 1809 mildly and moderately DN were diagnosed from 2010 through 2011. In all, 765 (42.3%) of these lesions were found to have positive surgical margins during biopsy, and 495 (64.7) of the 765 lesions were subsequently re-excised. Melanocytic residuum was present in 18.2% of re-excisional specimens. Re-excision resulted in a clinically significant alteration of the diagnosis in only 1 case (0.2%).
Limitations |
Limitations include retrospective design and inability to assess for malignant transformation given limited follow-up.
Conclusions |
Re-excising mildly and moderately DN results in a low histopathological yield and rarely results in a clinically significant change in diagnosis. As such, clinical monitoring of margin-positive lesions may be warranted.
Le texte complet de cet article est disponible en PDF.Key words : dermatopathology, dysplastic nevus, melanoma, nevus, pigmented lesions, surgical management
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
Vol 71 - N° 6
P. 1071-1076 - décembre 2014 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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