Epstein–Barr virus: Dermatologic associations and implications : Part I. Mucocutaneous manifestations of Epstein–Barr virus and nonmalignant disorders - 13/12/14
Abstract |
Epstein–Barr virus (EBV) is a ubiquitous virus that has been implicated in a wide range of human diseases, many of which have mucocutaneous manifestations. As a member of the herpesviridae family, EBV causes lifelong infection by establishing latency in B lymphocytes. An intact immune response is critical in preventing progression of EBV disease, and the clinical manifestations of infection are dependent on the intricate relationship between virus and host immune system. This review provides a comprehensive overview of the epidemiology, pathophysiology, and diagnostic testing in EBV infection. In part I of this continuing medical education article, the mucocutaneous manifestations of EBV infection are reviewed with an emphasis on pathophysiology and management.
Le texte complet de cet article est disponible en PDF.Key words : Epstein-Barr virus, human herpes virus 4, latency, infectious mononucleosis, papular acrodermatitis of childhood, oral hairy leukoplakia, hydroa vacciniforme, nonsexually related acute genital ulcers, histiocytic necrotizing lymphadenitis, lymphoproliferative, heterophile antibodies
Abbreviations used : CAEBV, CMV, EA, EBV, EBER, EBNA, GCS, HMB, HV, IM, ISH, KFD, LC, LCL, LMP, NRAGU, NF-κB, OHL, PCR, PTLD, STAT1, VCA
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
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Date of release: January 2015 |
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Expiration date: January 2018 |
Vol 72 - N° 1
P. 1-19 - janvier 2015 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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