Epstein–Barr virus: Dermatologic associations and implications : Part II. Associated lymphoproliferative disorders and solid tumors - 13/12/14
Abstract |
Epstein–Barr virus (EBV) was the first human virus to be associated with oncogenesis. Over the past few decades, cumulative research has revealed that latent EBV infection may be implicated in the pathogenesis of a heterogeneous group of lymphoproliferative disorders and malignancies occurring in both immunocompetent and immunocompromised hosts. Many of these diseases have either primary or secondary cutaneous manifestations. Serologic studies and EBV-encoded RNA in situ hybridization stains have been used to show the association of EBV with disease; while these findings may imply a role, they do not equate with causation. In part II of this continuing medical education review, the salient features of EBV-associated lymphoproliferative disorders and solid tumors are detailed.
Le texte complet de cet article est disponible en PDF.Key words : angioimmunoblastic T-cell lymphoma, Burkitt lymphoma, diffuse large B-cell lymphoma, Epstein–Barr virus, gastric carcinoma, hemophagocytic syndrome, Hodgkin lymphoma, hydroa vacciniforme–like lymphoma, leiomyosarcoma, lymphomatoid granulomatosis, nasopharyngeal carcinoma, NK/T-cell lymphoma, posttransplant lymphoproliferative disorder
Abbreviations used : AITL, BL, CAEBV, DLBCL, EBER, EBNA, EBV, ENK/T, HL, HPS, HRS, HV, HVLL, ISH, LMP1, LYG, MF, NHL, PCR, PTLD, SPTCL, TIA-1, VCA
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
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Date of release: January 2015 |
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Expiration date: January 2018 |
Vol 72 - N° 1
P. 21-34 - janvier 2015 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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