Use of Traditional and Atypical Neuroleptics in Therapy of Psychoses Caused by Use of Synthetic Drugs - 09/06/15
Résumé |
Introduction |
Onset as a result of use of new synthetic drugs of behavioral disorders accompanied by disorders of perception, consciousness and aggression is the basic reason for seeking specialized help.
Objective |
to compare efficiency of Haloperidol and Clopixol-Acuphase (zuclopenthixol acetate) in therapy of acute psychotic disorders caused by use synthetic cannabinoids.
Material and Methods |
72 patients (mean age 23,7±2,4) admitted with acute psychotic disorders due to use of synthetic cannabinoids were examined. In the course of investigation patients were divided into two groups: group 1 (n=37) with haloperidol for stopping of psychotic disorders, group 2 (n=35) with Clopixol-Acuphase. Detoxification and metabolic therapy were administered.
Results |
The carried-out analysis showed that when using the typical neuroleptic haloperidol in patients of group 1 the reduction of psychomotor excitement passed for 8±2,5 hours; stopping of hallucinatory manifestations was observed after 48±12,0 hours; in the same period there was Self-identification restoration (who had such disturbance), orientation was restored for 72±8 hours; delusional disorders disappeared after 3-5 days. When using Clopixol-Acuphase psychomotor excitement was reduced after 4±1,5 hours, stopping of hallucinatory disorders occurred at the same time with Self-identification restoration in average after 36±8 hours, orientation in place and time was restored for 48±12 hours, delusional disorders disappeared within 72 hours.
Discussion |
The assessment of efficiency of therapy of acute psychoses caused by use of new synthetic cannabinoids showed that use of Clopixol-Acuphase allows to cope quicker with psychomotor excitement and hallucinatory disorders which represent a substantial danger to the patient and people around.
Le texte complet de cet article est disponible en PDF.Vol 30 - N° S1
P. 489 - mars 2015 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?