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Journal of the American Academy of Dermatology
Volume 74, n° 2
pages 215-228 (février 2016)
Doi : 10.1016/j.jaad.2015.04.059
accepted : 22 April 2015
Continuing Medical Education

Neurocutaneous disease : Neurocutaneous dysesthesias

Nora K. Shumway, MD a, Emily Cole, MD b, Kristen Heins Fernandez, MD a,
a Department of Dermatology, University of Missouri, Columbia, Missouri 
b School of Medicine, University of Missouri, Columbia, Missouri 

Correspondence to: Kristen Heins Fernandez, MD, Department of Dermatology, 1 Hospital Dr, MA 111, Columbia, MO 65212.

Dysesthesia is a generic term for a cutaneous symptom—such as pruritus, burning, tingling, stinging, anesthesia, hypoesthesia, tickling, crawling, cold sensation, or even pain—without a primary cutaneous condition in a well-defined location that is often caused by nerve trauma, impingement, or irritation. There are multiple types of dysesthesias depending on the body location and the nerves involved. While location, exact symptoms, and etiologies might vary, the underlying theme is that these conditions are of neurologic origin and have dermatologic consequences. For many of these conditions, the symptoms are localized to the skin, and patients frequently present to the dermatologist; it is important for dermatologists to be knowledgeable about these symptoms and their underlying causes. In part II of this continuing medical education review, the primary diagnoses associated with underlying cutaneous dysesthesias will be explored, including scalp dysesthesia, trigeminal trophic syndrome, meralgia paresthetica, notalgia paresthetica, and brachioradial pruritus. The typical demographics in terms of symptoms, location, and patient populations will be discussed in addition to the specific etiologies, workups, and possible treatment options.

The full text of this article is available in PDF format.

Key words : brachioradial pruritus, burning scalp syndrome, dysesthesia, macular amyloidosis, meralgia paresthetica, neurocutaneous, notalgia paresthetica, scalp dysesthesia, trigeminal trophic syndrome

Abbreviations used : ASIS, BRP, LFCN, MP, NP, OMT, TENS, TTS

 Funding sources: None.
 Conflicts of interest: None declared.
 Date of release: February 2016
 Expiration date: February 2019

© 2015  Published by Elsevier Masson SAS.
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