Coagulation disorders and their cutaneous presentations: Diagnostic work-up and treatment - 14/04/16
Abstract |
Both inherited and acquired hypercoagulable states can present with nonspecific clinical manifestations, such as petechiae, purpura, livedo reticularis, and ulcerations. A good history and physical examination are crucial to diagnoses of these conditions. Inherited conditions tend to present either in neonatal period or later in life, while acquired conditions typically occur later in life. Diagnostic studies are performed to identify the coagulation cascade deficiency or defect. Treatment primarily hinges on anticoagulation and wound care. In this article, we provide an in-depth analysis of the clinical manifestations, diagnostic considerations, and management options of patients in hypercoagulable states.
Le texte complet de cet article est disponible en PDF.Key words : factor V Leiden mutation, hypercoagulable state, hyperhomocysteinemia, livedoid vasculopathy, protein C deficiency, protein S deficiency, thrombophilia, thrombosis, ulcers, warfarin necrosis
Abbreviations used : AB, APC, APS, AT, ATIIID, DVT, ELISA, FVL, FVLM, HIT, HS, INR, LE, LMWH, LV, PCR, PT, PTT, SCD, TTP, VTE
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
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Date of release: May 2016 |
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Expiration date: May 2019 |
Vol 74 - N° 5
P. 795-804 - mai 2016 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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