Use of tumor necrosis factor (TNF) inhibitors in patients with HIV/AIDS - 14/04/16
Abstract |
Patients with HIV and AIDS are living longer because of advancements in antiretroviral therapy. These patients are often susceptible to debilitating inflammatory disorders that are refractory to standard treatment. We discuss the relationship of tumor necrosis factor-alpha and HIV and then review 27 published cases of patients with HIV being treated with tumor necrosis factor-alpha inhibitors. This review is limited because no randomized controlled trials have been performed with this patient population. Regardless, we propose that reliable seropositive patients, who are adherent to medication regimens and frequent monitoring and have failed other treatment modalities, should be considered for treatment with tumor necrosis factor-alpha inhibitors.
Le texte complet de cet article est disponible en PDF.Key words : AIDS, autoimmune disease, hidradenitis suppurativa, HIV, inflammatory bowel disease, opportunistic infections, psoriasis, rheumatoid arthritis, tumor necrosis factor-alpha
Abbreviations used : ART, HCV, TNF
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
Vol 74 - N° 5
P. 974-980 - mai 2016 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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