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European Geriatric Medicine
Volume 7, n° 3
pages 207-213 (juin 2016)
Doi : 10.1016/j.eurger.2015.12.001
Received : 15 September 2015 ;  accepted : 2 December 2015
Vitamin D in sarcopenia: Understanding its role in pathogenesis, prevention and treatment
 

G. Arik , Z. Ulger
 Department of Internal Medicine, Division of Geriatric Medicine, Gazi University, Ankara, Turkey 

Tel.: +90 0312 2025070.
Abstract

Vitamin D has a well-known critical role in calcium and bone homeostasis. In recent years, there has been an increased interest in the potential regulatory role of vitamin D on metabolic pathways implicated in muscle functions. Evidence coming from epidemiologic studies has demonstrated that poor vitamin D status is associated with worse muscle functions. However, whether vitamin D deficiency and supplementation has a role on sarcopenia is not fully known. This review will focus on current knowledge and emerging data regarding the role of vitamin D in muscle functions and sarcopenia.

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Keywords : Vitamin D, Sarcopenia, Muscle, Strength, Physical performance

Abbreviations : IGF-1, VDR, PTH, 25OHD, GLUT4, RCTs, ng/mL, nmol/L, IU, IU/d




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