Assessment of the risk of cardiovascular disease in patients with rosacea - 20/07/16
, Peter R. Hansen, MD, PhD, DMSci b, Gunnar H. Gislason, MD, PhD b, c, d, Jacob P. Thyssen, MD, PhD, DMSci aAbstract |
Background |
Recent studies have shown a higher prevalence of cardiovascular (CV) risk factors in patients with rosacea. However, it remains unknown whether rosacea represents an independent CV risk factor.
Objective |
We evaluated the risk of myocardial infarction, stroke, CV death, major adverse CV events, and all-cause mortality, respectively.
Methods |
Between January 1, 1997, and December 31, 2012, a total of 4948 patients with rosacea were identified and matched with 23,823 control subjects. We used Poisson regression to calculate incidence rate ratios.
Results |
Adjusted incidence rate ratios were 0.75 (95% confidence intervals [CI] 0.57-1.00) for myocardial infarction, 1.08 (95% CI 0.86-1.35) for ischemic stroke, 1.01 (95% CI 0.61-1.67) for hemorrhagic stroke, 0.99 (95% CI 0.80-1.24) for CV death, 0.99 (95% CI 0.86-1.15) for major adverse CV events, and 0.95 (95% CI 0.85-1.06) for all-cause mortality.
Limitations |
We were unable to distinguish between the different subtypes and severities of rosacea.
Conclusions |
In this population-based study, rosacea was not associated with increased risk of adverse CV outcomes or death.
Le texte complet de cet article est disponible en PDF.Key words : cardiovascular disease, epidemiology, risk factors, rosacea
Abbreviations used : CI, CV, MACE, MI
Plan
| Funding sources: None. |
|
| Disclosure: Dr Hansen is supported by a grant from the LEO Foundation. Dr Gislason is supported by an unrestricted research scholarship from the Novo Nordisk Foundation. Dr Egeberg is a former employee of Pfizer. Dr Thyssen has been paid by Galderma to teach about facial dermatoses and is supported by an unrestricted grant from the Lundbeck Foundation. This research was performed independently through the authors' academic university affiliations. |
Vol 75 - N° 2
P. 336-339 - août 2016 Retour au numéro
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