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Sous presse. Epreuves corrigées par l'auteur. Disponible en ligne depuis le lundi 14 novembre 2016
Doi : 10.2515/therapie/2015056
Received : 6 June 2015 ;  accepted : 24 July 2015
Cardiac arrests associated with low plasma and tissue levels of local anaesthetics
Arrêts cardiaques associés à de faibles niveaux plasmatiques et tissulaires d’anesthésiques locaux

Joachim Alexandre a, b, c, Xavier Humbert d, Marion Sassier a, Alexandre Cesbron a, Cécile Le Naourès e, Véronique Pottier f, Paolo-Emilio Puddu g, Paul Milliez b, c, h, Antoine Coquerel a, c, i, , Sophie Fedrizzi a
a CHU de Caen, Department of Pharmacology, avenue de la Côte-de-Nacre, CS 30001, 14033 Caen cedex 9, France 
b Université de Caen Basse-Normandie, EA 4650 Signalisation, électrophysiologie et imagerie des lésions d’ischémie-reperfusion myocardique, 14032 Caen, France 
c Université de Caen Basse-Normandie, Medical School, 14032 Caen, France 
d CHU de Caen, Department of General Medicine, 14033 Caen, France 
e CHU de Caen, Department of Pathology, 14033 Caen, France 
f CHU de Caen, Department of Anesthesiology, 14033 Caen, France 
g Department of Cardiovascular Sciences, Sapienza University, 00185 Roma, Italy 
h CHU de Caen, Department of Cardiology, 14033 Caen, France 
i Université de Caen Basse-Normandie, Inserm U 1075, COMETE, 14032 Caen, France 

Corresponding author at: CHU de Caen, Department of Pharmacology, avenue de la Côte-de-Nacre, CS 30001, 14033 Caen cedex 9, France.

Keywords : Local anaesthetics, Cardiac arrest, Cardiac toxicity, French pharmacovigilance database

Mots clés : Anesthésiques locaux, Arrêt cardiaque, Toxicité cardiaque, Banque nationale de pharmacovigilance

 This case was notified to the Centre Régional de Pharmacovigilance de Basse-Normandie in January 6th, 2014 and then registered in the French Pharmacovigilance Database (FPD).

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