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Archives of cardiovascular diseases
Volume 110, n° 4
page 274 (avril 2017)
Doi : 10.1016/j.acvd.2017.02.004
Received : 28 February 2017 ;  accepted : 28 February 2017
Letters to the editor

Answer to the letter of Reza Pakzad and Saeid Safiri
Réponse à la lettre de Reza Pakzad and Saeid Safiri
 

Scott J. Dankel, Jeremy P. Loenneke, Paul D. Loprinzi
 Department of Health, Exercise Science and Recreation Management, University of Mississippi, Mississippi, USA 

Corresponding author.

Keywords : Epidemiology, Health promotion, NHANES, Methodology

Mots clés : Épidémiologie, Promotion de la santé, Institut NHANES, Méthodologie


We thank you for the opportunity to respond to the letter by Drs. Pakzad and Safiri. We appreciate their interest in our paper but find their letter unwarranted. First, it is not the intent of all survival analyses to evaluate all-cause mortality as the outcome strictly for statistical power or sample size issues. As indicated by Pakzad and Safiri, survival-based analyses could fit hierarchical models if indeed there was an interest to evaluate numerous cause-specific outcomes, which was not of interest in our study. The second issue raised by Pakzad and Safiri is that we did not compute adjusted analyses to evaluate the “independent” association of muscle-strengthening activities on mortality. This appears to be an oversight by Pakzad and Safiri, as our analysis section indicates that we employed adjusted models to evaluate the independent association of muscle-strengthening activities on mortality. Lastly, Pakzad and Safiri indicated that we did not evaluate the proportional hazard assumption, and thus indicate that our findings may be incorrect or misleading. However, the second paragraph of our results section indicates that this proportional hazard assumption was not violated in our analyses.

Disclosure of interest

The authors declare that they have no competing interest.



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