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Journal of the American Academy of Dermatology
Volume 14, n° 5P1
pages 777-784 (mai 1986)
Doi : 10.1016/S0190-9622(86)70093-5
accepted : 7 January 1986
A therapeutic approach to venous ulcers

Vincent Falanga, M.D. , William H. Eaglstein, M.D.
University of Pittsburgh School of Medicine, Department of Dermatology. 

aReprint requests to: Dr. Vincent Falanga, 3601 Fifth Ave., Pittburgh, PA 15213.

Recent progress in the understanding of the pathogenesis of venous ulcers and in the biology of healing allows us to formulate a therapeutic strategy for patients with venous ulcerations. Systemic evaluation and local considerations of the ulcerated areas are important in the management of these patients. Occlusive therapy, made easier by new and more effective dressings, relieves pain, leads to better and faster healing in a moist environment, and facilitates treatment in the ambulatory setting. Fibrinolytic therapy, aimed at reducing pericapillary fibrin and restoring proper physiologic exchanges between blood and tissues, may benefit some patients with extensive and nonhealing ulcers.

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