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Journal of the American Academy of Dermatology
Volume 14, n° 5P1
pages 785-791 (mai 1986)
Doi : 10.1016/S0190-9622(86)70094-7
Cyclosporin A

Elizabeth Heller Page, M.D., Denise M. Wexler, M.D., F.R.C.P.(C), Lyn C. Guenther, M.D., F.R.C.P.(C)
Department of Dermatology, University of Western Ontario. 

aReprint requests to: Dr. Lyn C. Guenther, 215 Wellington St., London, Ontario N6B 2L2, Canada.

Cyclosporin A is a new immunosuppressive agent that selectively affects T helper cells without suppressing the bone marrow. Cyclosporin A. has been used primarily to prevent rejection in organ transplantation and acute graftversus-host disease. Studies suggest that it may be of benefit in psoriasis, pemphigus vulgaris, bullous pemphigoid, Behçet's disease, and collagen vascular disorders. Since cyclosporin A has a potentially important use in dermatology, and since a number of dermatologic side effects are seen as a consequence of its use, it is important that dermatologists be familiar with this drug.

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