Article

Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text
Advertising


Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates



Journal of the American Academy of Dermatology
Volume 14, n° 5P1
pages 815-826 (mai 1986)
Doi : 10.1016/S0190-9622(86)70099-6
Papulonecrotic tuberculid: A neglected disease in Western countries
 

Edward Wilson-Jones, F.R.C.P., F.R.C(Path) , Richard K. Winkelmann, M.D., Ph.D., F.R.C.P.
Institute of Dermatology, University of London, and the Mayo Clinic and Mayo Foundation, Rochester 

aReprint requests to: Dr. E. Wilson-Jones, Institute of Dermatology, St. John's Hospital for Diseases of the Skin, 5 Lisle St., Leicester Square, London, WC2H 7BJ, England.
@@#100979@@

Papulonecrotic tuberculid was diagnosed in twelve young patients demonstrating symmetric scattered papulopustular necrotic lesions of the extremities. The diagnosis was supported by a strongly positive Mantoux reaction in all cases, evidence of preexisting or past tuberculosis in eight patients, characteristic histologic findings, and a prompt resolution with antituberculosis therapy. Recurrence of the skin lesions in three patients treated only with isoniazid or with para-aminosalicylic acid and isoniazid indicates the necessity for combination treatment with several antituberculosis drugs. A detailed study of twenty biopsies indicates that the primary lesion is a subacute lymphohistiocytic vasculitis that causes thrombosis and destruction of small dermal vessels. These changes lead to an infarctlike lesion with coagulation necrosis of dermal tissue. In eleven instances a well-marked palisaded histiocytic reaction was seen around necrotic areas, calling into question the differential diagnosis of granuloma annulare or Churg-Strauss granulomatosis.

The full text of this article is available in PDF format.

 Supported in part by the Eleanor Naylor Dana Charitable Trust and the Kieckhefer Foundation


Top of the page

© 1986  Published by Elsevier Masson SAS.
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Close
Article Outline
You can move this window by clicking on the headline
@@#110903@@