In a double-blind, parallel trial which lasted 1 week and comprised eighty-eight patients, a study of the response to topical therapy of the infected component of four common eczematous processes showed that the treatment outcome with corticosteroid antimicrobial creams was not influenced by the type of dermatitis. The cream with fluocinonide 0.05% was significantly better than the cream with triamcinolone 0.1%. Both creams were clinically superior to a cream containing only the antimicrobial agents but exerted a similar antimicrobial activity.