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Journal of the American Academy of Dermatology
Volume 4, n° 4
pages 451-457 (avril 1981)
Doi : 10.1016/S0190-9622(81)70046-X
Clinical and Laboratory Studies

Lymphoma-associated papulosis: Lymphomatoid papulosis associated with lymphoma

S. Randy Scheen, M.D. , 1, John A. Doyle, M.B. 1, R.K. Winkelmann, M.D., Ph.D. 1
Rochester, MN, USA 

*Reprint requests to: Dr. S. R. Scheen III, c/o Section of Publications, Mayo Clinic, Rochester, MN 55905.

Lymphomatoid papulosis is a condition characterized by the continuing appearance of self-healing inflammatory papulonodules which histologically show atypical cells simulating a malignant process. We describe two patients who had features typical of lymphomatoid papulosis in whom a lymphoreticular malignancy developed. The first patient developed Hodgkin's disease 30 years after the onset of lesions that resembled lymphomatoid papulosis, and the second patient developed a lymphocytic lymphoma 11 months after the appearance of the self-healing papules. While most patients with lymphomatoid papulosis have a benign protracted course, “lymphoma-associated papulosis” represents the malignant end of this spectrum, in which lymphomatoid papulosis is associated with a lymphoma. All patients with lymphomatoid papulosis require close, long-term follow-up.

The full text of this article is available in PDF format.
1  From the Department of Dermatology, Mayo Clinic and Mayo Foundation.

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