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Journal of the American Academy of Dermatology
Volume 4, n° 5
pages 537-540 (mai 1981)
Doi : 10.1016/S0190-9622(81)70052-5
Clinical and laboratory study

Vascular response in halo of recent halo nevus
 

Alexander Berman, M.D. , 1, Sidney Herszenson, M.D. 1
Milwaukee, WI, USA 

*Reprint requests to: Dr. Alexander Berman, Milwaukee Skin Center, 7400 W. Brown Deer Road, Milwaukee, WI 53223.
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The depigmented halo of a recently acquired halo nevus showed prominent erythema. Microscopic examination of a specimen from the halo showed dilatation of the dermal blood vessels, thickening of the vessel walls, and swelling of the endothelial cells; cellular infiltration was totally absent. Direct immunofluorescent studies on skin from the halo failed to show vessel, basement membrane, or intercellular fluorescence with IgG, IgM, IgA, C3 , and fibrin. We conclude that the erythema in the skin of the depigmented halo is the result of dilated dermal blood vessels and that the mechanism of vascular dilatation is not associated with direct infiltration by inflammatory cells nor with immune complex formation. Erythema in the skin of the depigmented halo has not, to our knowledge, been studied previously.

The full text of this article is available in PDF format.
1  From the Milwaukee Skin Center.

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