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Journal of the American Academy of Dermatology
Volume 4, n° 5
pages 541-543 (mai 1981)
Doi : 10.1016/S0190-9622(81)70053-7
Clinical and laboratory study

Dacarbazine-induced photosensitivity reaction

Cheuk W. Yung, M.D. , 1, Evonne M. Winston, M.D. 1, Allan L. Lorincz, M.D. 1
Chicago, IL, USA 

Reprint requests to: Dr. Cheuk W. Yung, Section of Dermatology, Department of Medicine, The University of Chicago, 950 East 59th St., Box 409, Chicago, IL 60637.

Dacarbazine (DTIC-Dome) is a widely used chemotherapeutic agent employed in the therapy of malignant melanoma. In this communication, we present two patients who developed photosensitivity skin reactions immediately after its administration. Physicians using dacarbazine should be aware of this side effect and should instruct patients to avoid solar exposure following infusions of this drug.

The full text of this article is available in PDF format.

* DTIC-Dome. Dome Division, Miles Laboratories, Inc., supported the reproduction of the color photographs in this article.

1  From the Section of Dermatology, Department of Medicine, The University of Chicago Pritzker School of Medicine.

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