Article

Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text
Advertising


Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates



Journal of the American Academy of Dermatology
Volume 4, n° 5
pages 547-555 (mai 1981)
Doi : 10.1016/S0190-9622(81)70055-0
Clinical and laboratory study

Penicillamine-associated pemphigus: Is it really pemphigus?
 

James L. Troy, M.D. , 1, David N. Silvers, M.D. 1, Marc E. Grossman, M.D. 1, Israeli A. Jaffe, M.D. 1
New York, NY, USA 

*Reprint requests to: Dr. James L. Troy, Dermatopathology Section, Suite 7 J, New York University Medical Center, 530 First Ave., New York, NY 10016/212-340-7250.
@@#100979@@

Penicillamine-associated bullous eruptions share with spontaneously occurring pemphigus intraepidermal acantholysis, epidermal intercellular deposition of immunoglobulin, and circulating serum antibody against the intercellular regions of the epidermis. We report the case of a penicillamine-associated bullous eruption in which there were some of the histologic features of pemphigus, but none of the imrnunofluorescent features. Instead, the immunofluorescent findings of bullous pemphigoid were demonstrated. Review of the literature reveals that clinical and histologic features of penicillamine-associated bullous eruptions differ in important respects from those of spontaneously occurring pemphigus. Our report adds immunologic data to evidence that the penicillamine-associated bullous eruptions may not be the same disease as spontaneously occurring pemphigus.

The full text of this article is available in PDF format.
1  From the Departments of Dermatology, Pathology, and Medicine, the College of Physicians and Surgeons of Columbia University, and the Presbyterian Hospital.

Top of the page

© 1981  Published by Elsevier Masson SAS.
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Close
Article Outline
You can move this window by clicking on the headline
@@#110903@@