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Journal of the American Academy of Dermatology
Volume 2, n° 4
pages 285-294 (avril 1980)
Doi : 10.1016/S0190-9622(80)80040-5
Clinical and laboratory studies

Dermatophytosis in patients with chronic mucocutaneous candidiasis

Steven K. Shama, M.D., Charles H. Kirkpatrick, M.D.
 From the Dermatology Branch, National Cancer Institute, National Institutes of Health, and the Laboratory of Clinical Investigation, National Institute of All Infectious Diseases, National Institutes of Health, USA 

1Reprint requests to: Dr. Charles H. Kirkpatrick, National Jewish Hospital & Research Center, 3800 East Colfax Ave., Denver, CO 80206/303-388-4461.

We review the association of concurrent dermatophyte infections in patients with chronic mucocutaneous candidiasis and add twelve new patients to the seventeen previously reported ones. In sixty patients with chronic mucocutaneous candidiasis studied at the National Institutes of Health (NIH), twelve (20%) also had significant local or diffuse dermatophytosis. A comparison between candidiasis patients with and without dermatophytosis revealed no significant differences in their distribution within the various clinical syndromes of chronic mucocutaneous candidiasis nor in the immunologic responses that were tested. Failure to recognize coexistent dermatophytosis in candidiasis patients may lead to unsatisfactory responses to treatment.

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