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Journal of the American Academy of Dermatology
Volume 4, n° 2
pages 205-230 (février 1981)
Doi : 10.1016/S0190-9622(81)70024-0
Clinical review

Some recent advances in HLA and skin diseases

Akira Ozawa, M.D. , 1, Muneo Ohkido, M.D. 1, Kimiyoshi Tsuji, M.D. 1
a Augusta, GA, USA 
b Isehara, Kanagawa, Japan 

*Reprint requests to: Dr. Akira Ozawa, Department of Dermatology, School of Medicine, Tokai University, Bohseidai, Isehara, Kanagawa 259-11, Japan.

During the past 15 years, much has been learned about the human major histocompatibility complex. These new findings have been applied to the whole field of medicine, including transplantation immunology, blood transfusions, association with disease, human genetics, and the mechanism of human immune responses. In clinical medicine, the association between the major histocompatibility complex and various diseases has attracted the greatest interest. In this paper, we summarize the basic information on the human histocompatibility complex and its association with dermatologic disorders. Data from the world literature are reviewed and tabulated. Our own investigations on psoriasis, atopic dermatitis, and epidermolysis bullosa are discussed in detail.

The full text of this article is available in PDF format.
1  From the Department of Dermatology, Medical College of Georgia, and the Department of Dermatology and Transplantation Immunology Center, School of Medicine, Tokai University.

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