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Journal of the American Academy of Dermatology
Volume 3, n° 3
pages 271-279 (septembre 1980)
Doi : 10.1016/S0190-9622(80)80190-3
Clinical and laboratory studies

Morphea and lichen sclerosus et atrophicus : Clinical and histopathologic studies in patients with combined features
 

Jouni Uitto, M.D., Ph.D. a, b, , *, Daniel J. Santa Cruz, M.D. a, b, Eugene A. Bauer, M.D. a, b, **, Arthur Z. Eisen, M.D. a, b
a From the Division of Dermatology, Department of Medicine, Washington University School of Medicine, USA 
b The Division of Surgical Pathology, Department of Pathology, Washington University School of Medicine, USA 

1Reprint requests to: Dr. Jouni Uitto, Division of Dermatology, Department of Medicine, Harbor-UCLA Medical Center, 1000 W. Carson St., Torrance, CA 90509.
Abstract

Ten patients with skin lesions clinically consistent with morphea and lichen sclerosus et atrophicus were studied. In all cases, histopathologic changes of both morphea and lichen sclerosus et atrophicus were also present. The coexistence of morphea and lichen sclerosus et atrophicus in the same patient suggests that these lesions represent a spectrum which may reflect similar etiologic events or closely related pathologic processes in these two diseases.

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*** Supported in part by United States Public Health Service, National Institutes of Health grants TO-AM 07284, AM 12129, AM 19537, AM 27123, and RR 00036, and by a grant from the National Foundation—March of Dimes.
**** We thank Drs. Morris D. Marcus, Eugenia T. Poulos, John A. Powell, and Lester T. Reese for referring patients to this study. We also thank Dr. Robert W. Ogilvie for histologic slides on Patient 3.

*  Present address: Division of Dermatology, Harbor-UCLA Medical Center, Torrance, CA 90509; recipient of Research Career Development Award 7-KO4-AM-00897 from the National Institutes of Health.
**  Recipient of Research Career Development Award 5-KO4-AM-00077 from the National Institutes of Health.

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