Pulsed dye laser treatment of telangiectases with and without subtherapeutic sclerotherapy : Clinical and histologic examination in the rabbit ear vein model - 12/10/17

Doi : 10.1016/0190-9622(90)70180-P

Mitchel P. Goldman, MD ^{^{1
From the Division of Dermatology, Department of Medicine, University of California School of Medicine.},}^⁎, Dale E. Martin, MD ^{^{1
From the Division of Dermatology, Department of Medicine, University of California School of Medicine.}}, Richard E. Fitzpatrick, MD ^{^{1
From the Division of Dermatology, Department of Medicine, University of California School of Medicine.}}, Javier Ruiz-Esparza, MD ^{^{1
From the Division of Dermatology, Department of Medicine, University of California School of Medicine.}}
San Diego, California, USA

^†Reprint requests: Mitchel P. Goldman, MD, 850 Prospect St., La Jolla, CA 92037.

Abstract

The treatment of leg telangiectases with the carbon dioxide or argon laser results in a low success rate and an unacceptable risk of scarring. Sclerotherapy is effective; however, pigmentation and telangiectatic matting induced by extravasation of RBCs and excessive posttreatment inflammation are common. We conducted a clinical and histologic study of therapy with the 585 nm pulsed dye laser alone and in combination with subtherapeutic sclerotherapy in the rabbit ear vein model. The pulsed dye laser alone was effective when 10 joule/cm² was used. In combination with immediate injection of the sclerosant, effective endosclerosis occurred with all tested laser energies (8 to 10 joule/cm²).

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*	Supported in part by Candela Laser Corp., Wayland, Mass.
**	Presented in part at the Sixteenth Annual Meeting of the American Society for Dermatologie Surgery, Ft. Lauderdale, Fla., March 8, 1989; the Ninth Annual Meeting of the American Society for Laser Medicine and Surgery, Arlington, Va., April 16, 1989; and the Forty-eighth Annual Meeting of the American Academy of Dermatology, San Francisco, Calif., Dec. 2—7, 1989.

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Vol 23 - N° 1

P. 23-30 - juillet 1990 Retour au numéro

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Pulsed dye laser treatment of telangiectases with and without subtherapeutic sclerotherapy : Clinical and histologic examination in the rabbit ear vein model - 12/10/17

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