Low-dose weekly methotrexate for unusual neutrophilic vascular reactions: Cutaneous polyarteritis nodosa and Behçeťs disease - 12/10/17
Doi : 10.1016/0190-9622(91)70156-V
Joseph L. Jorizzo, MD a, ⁎, Wain L. White, MD a, b, Christopher M. Wise, MD c, Michael D. Zanoffi, MD a, Elizabeth F. Sherertz, MD a
a From the Department of Dermatology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA
b From the Department Pathology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA
c From the Department of Internal Medicine, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA
*Reprint requests: Joseph L. Jorizzo, MD, Dept. of Dermatology, Bowman Gray School of Medicine, Wake Forest University, 300 S. Hawthorne Rd., Winston-Salem, NC 27103.
Résumé |
Low-dose weekly methotrexate therapy has been used to treat patients with psoriasis for more than 20 years. This regimen has also been used to treat rheumatoid arthritis, inflammatory bowel disease, primary sclerosing cholangitis, and corticosteroid-dependent asthma. We report two patients with Behçeťs disease with cutaneous neutrophilic vascular reactions and three with cutaneous polyarteritis nodosa who responded dramatically to low-dose weekly methotrexate therapy.
Le texte complet de cet article est disponible en PDF.© 1991
Publié par Elsevier Masson SAS.
Vol 24 - N° 6P1
P. 973-978 - juin 1991 Retour au numéro
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