Accuracy of dermatoscopy for the diagnosis of nonpigmented cancers of the skin - 23/11/17
Abstract |
Background |
Nonpigmented skin cancer is common, and diagnosis with the unaided eye is error prone.
Objective |
To investigate whether dermatoscopy improves the diagnostic accuracy for nonpigmented (amelanotic) cutaneous neoplasms.
Methods |
We collected a sample of 2072 benign and malignant neoplastic lesions and inflammatory conditions and presented close-up images taken with and without dermatoscopy to 95 examiners with different levels of experience.
Results |
The area under the curve was significantly higher with than without dermatoscopy (0.68 vs 0.64, P < .001). Among 51 possible diagnoses, the correct diagnosis was selected in 33.1% of cases with and 26.4% of cases without dermatoscopy (P < .001). For experts, the frequencies of correct specific diagnoses of a malignant lesion improved from 40.2% without to 51.3% with dermatoscopy. For all malignant neoplasms combined, the frequencies of appropriate management strategies increased from 78.1% without to 82.5% with dermatoscopy.
Limitations |
The study deviated from a real-life clinical setting and was potentially affected by verification and selection bias.
Conclusions |
Dermatoscopy improves the diagnosis and management of nonpigmented skin cancer and should be used as an adjunct to examination with the unaided eye.
Le texte complet de cet article est disponible en PDF.Key words : dermatoscopy, dermoscopy, diagnosis, keratinocytic skin cancer, melanoma, nonpigmented skin cancer
Abbreviations used : AUC, CI, IDS
Plan
Funding sources: None. |
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Disclosure: Dr Soyer is a shareholder of e-derm consult GmbH and MoleMap by Dermatologists Ltd Pty, and he provides teledermatologic reports regularly for both companies. Drs Sinz, Tschandl, Rosendahl, Akay, Argenziano, Blum, Braun, Cabo, Gourhant, Kreusch, Lallas, Lapins, Marghoob, Menzies, Paoli, Rabinovitz, Rinner, Scope, Thomas, Zalaudek, and Kittler have no conflicts of interest to declare. |
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Reprints not available from the authors. |
Vol 77 - N° 6
P. 1100-1109 - décembre 2017 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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