2 Iconography
Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text

Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates

Journal of the American Academy of Dermatology
Volume 77, n° 5
pages 911-919 (novembre 2017)
Doi : 10.1016/j.jaad.2017.04.1128
accepted : 27 April 2017
Dermatologic Surgery

Aesthetic outcome and complications of simple interrupted versus running subcuticular sutures in facial surgery: A randomized controlled trial

Xiaomeng Liu, MD a, b, c, , Patty J. Nelemans, PhD d, Lisa D.S. Frenk, MD e, Helma Sengers, MPA f, Stephania M.H. Tuinder, MD, PhD g, Peter M. Steijlen, MD, PhD a, b, f, Klara Mosterd, MD, PhD a, b, Nicole W.J. Kelleners-Smeets, MD, PhD a, b
a Department of Dermatology, Maastricht University Medical Centre, Maastricht, The Netherlands 
b GROW, School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands 
c Department of Dermatology, Flevo Hospital Almere, Almere, The Netherlands 
d Department of Epidemiology, Care and Public Health Research Institute, School for Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands 
e Department of Cardiology, Maastricht University Medical Centre, Maastricht, The Netherlands 
f Department of Dermatology, Catharina Hospital, Eindhoven, The Netherlands 
g Department of Plastic Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands 

Correspondence to: Xiaomeng Liu, MD, Department of Dermatology, Maastricht University Medical Centre, P. Debyelaan 25, 6229 HX Maastricht, The Netherlands.Department of Dermatology, Maastricht University Medical Centre, P. Debyelaan 25MaastrichtHX6229The Netherlands

The suturing technique and its associated complications could affect cosmetic outcome after facial surgery. Literature on this topic is limited.


To compare the cosmetic results 12 months after treatment and complications associated with simple interrupted sutures (SIS) versus running subcuticular sutures (RSS) in facial surgery.


A randomized, controlled multicenter trial was performed. Adults receiving dermatologic surgery on the face were randomized to receive SIS or RSS for wound closure. The primary outcome was the overall opinion score on the Patient and Observer Scar Assessment Scale (POSAS) 12 months after surgery. Secondary outcomes were the complication rates and scores according to alternative methods for assessment of cosmetic outcome. The observer of cosmetic outcome was blinded to treatment assignment.


142 patients were randomized to receive SIS (n = 73) or RSS (n = 69). Twelve months after surgery, the median score of the overall opinion on the POSAS was 2.0 (range 1-8) according to the patients and 3.0 (range 1-8) according to the observer in both groups. In the RSS group, hyper- or hypoesthesia was reported more often.


The cosmetic result was assessed by 1 observer.


SIS and RSS in facial surgery resulted in comparable cosmetic outcomes. RSS was more often associated with hyper- or hypoesthesia.

The full text of this article is available in PDF format.

Key words : aesthetic outcome, complications, cosmetic result, dermatologic surgery, POSAS, running subcuticular suture, simple interrupted suture, suturing technique, wound healing

Abbreviations used : ITT, MMS, OSAS, POSAS, PP, PSAS, RSS, SD, SIS

 Funding sources: Supported by Galderma Pharma SA.
 Conflicts of interest: None declared.
 Reprints not available from the authors.

© 2017  American Academy of Dermatology, Inc.@@#104156@@
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Article Outline