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Archives de pédiatrie
Volume 25, n° 3
pages 194-198 (avril 2018)
Doi : 10.1016/j.arcped.2017.12.002
Received : 8 February 2017 ;  accepted : 10 December 2017
Research Papers

Préparation et administration des médicaments dans les services de pédiatrie. Évaluation des pratiques des soignants
Drug administration to pediatric patients: Evaluation of the nurses’ preparation habits in pediatric units

S. Ménétré a, , M. Weber a, M. Socha a, c, S. Le Tacon b, I. May a, C. Schweitzer b, d, B. Demoré a, e
a Pôle pharmacie stérilisation, service pharmacie, hôpitaux de Brabois, CHRU de Nancy, allée du Morvan, 54511 Vandœuvre-Lès-Nancy, France 
b Pôle enfants néonatologie, hôpital d’Enfants, CHRU de Nancy, allée du Morvan, 54511 Vandœuvre-Lès-Nancy, France 
c CITHEFOR EA3452, faculté de pharmacie, université de Lorraine, rue Albert-Lebrun, 54001 Nancy cedex, France 
d DEVAH EA 3450, faculté de médecine, université de Lorraine, avenue de la Forêt-de-Haye, 54505 Vandœuvre-Lès-Nancy cedex, France 
e UMR 7565, SRSMC, CNRS, faculté de pharmacie, université de Lorraine, rue Albert-Lebrun, 54001 Nancy cedex, France 

Auteur correspondant.

In hospitals, the nursing staff is often confronted with the problem of the preparation and administration of drugs for their pediatric patients because of the lack of indication, pediatric dosage, and appropriate galenic form. The goal of this study was to give an overview of the nurses’ preparation habits in pediatric units and highlight their daily problems. This single-center prospective study was conducted through an observation of the nursing staff during the drug preparation process in medicine, surgery and intensive care units. We included 91 patients (55 boys and 36 girls), with an average age of 6.3 years (youngest child, 10 days old; oldest child, 18 years old). We observed a mean 2.16 drug preparations per patient [1–5]. We collected 197 observation reports regarding 66 injectable drugs and 131 oral drugs (71 liquid forms and 60 solid forms). The majority of these reports concerned central nervous system drugs (63/197), metabolism and digestive system drugs (50/197), and anti-infective drugs (46/197). The study highlights the nurses’ difficulties: modification of the solid galenic forms, lack of knowledge on oral liquid form preservation or reconstitution methods, withdrawal of small volumes, and vague and noncompliant labeling. This study led to the creation of a specific working group for pediatrics. This multidisciplinary team meets on a regular basis to work toward improving the current habits to both simplify and secure drug administration to hospitalized children.

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Keywords : Drug administration, Drug preparation, Central nervous system drugs, Metabolism and digestive system drugs, Anti-infective drugs

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