Basal cell carcinoma : Contemporary approaches to diagnosis, treatment, and prevention - 14/01/19

Doi : 10.1016/j.jaad.2018.02.083

Michael C. Cameron, MD ^a, Erica Lee, MD ^a, Brian P. Hibler, MD ^a, Cerrene N. Giordano, MD ^a, Christopher A. Barker, MD ^b, Shoko Mori, BS ^a, Miguel Cordova, MD ^a, Kishwer S. Nehal, MD ^a, Anthony M. Rossi, MD ^a,^⁎
^a Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York
^b Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York

^∗Address correspondence to: Anthony M. Rossi, MD, Division of Dermatology, Memorial Sloan Kettering Cancer Center, 16 E 60th St, 4th fl, New York, NY 10022.Division of DermatologyMemorial Sloan Kettering Cancer Center16 E 60th St, 4th flNew YorkNY10022

Abstract

As the most common human cancer worldwide and continuing to increase in incidence, basal cell carcinoma is associated with significant morbidity and cost. Continued advances in research have refined both our insight and approach to this seemingly ubiquitous disease. This 2-part continuing medical education series provides a comprehensive and contemporary review of basal cell carcinoma. The second article in this series will present both the current standard of care and newly developed approaches to diagnosis, treatment, and prevention of this disease.

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Key words : 5-fluorouracil, basal cell carcinoma, BCC, biopsy, confocal microscopy, hedgehog inhibitors, imiquimod, keratinocyte carcinoma, laser, Mohs micrographic surgery, multiphoton tomography, nonmelanoma skin cancer, optical coherence tomography, photodynamic therapy, prevention, radiation

Abbreviations used : 5-FU, AE, BCC, EDC, Hh, MMS, NCCN, OCT, OEBM, PDT, PNI, RCM, RCT, RT, sBCC, SSEPME

Plan

Standard of care in diagnosis

Novel noninvasive modalities in diagnosis

Standard of care in treating primary tumors

Treatment approaches in difficult and advanced disease

Quality of life and treatment in the elderly and disease follow-up and prevention

	Supported by National Institutes of Health/National Cancer Institute Cancer Center support grant P30 CA008748.
	Conflicts of interest: None declared.
	Date of release: February 2019
	Expiration date: February 2022