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Orthopaedics & Traumatology: Surgery & Research
Sous presse. Epreuves corrigées par l'auteur. Disponible en ligne depuis le dimanche 10 mars 2019
Doi : 10.1016/j.otsr.2019.01.007
Received : 27 June 2018 ;  accepted : 9 January 2019
Induced membrane technique in the treatment of infectious bone defect: A clinical analysis

Jianbing Wang 1, Qudong Yin 1, Sanjun Gu, Yongwei Wu, Yongjun Rui
 Department of Orthopaedics, Wuxi the Ninth People's Hospital Affiliated to Soochow University, No. 999 Liangxi Road, Wuxi 214062, Jiangsu, China 

Corresponding author.

At present, it is still a challenge for repairing a wide range of bone defect caused by various reasons. We aimed to investigate the effect of induced membrane technique in the treatment of infectious bone defect.

Patients and methods

The clinical data of twenty-one patients with infectious bone defect that received induced membrane technique treatment from January 2008 to August 2017 were collected for this study. The complications were recorded, and the bone defect healing and the recovery of joint function were evaluated by Paley method. The adjacent joint activities were also evaluated.


One month after the first stage of surgery, one case had wound dehiscence, and others healed well without infection. Six cases had induced membrane injury during the second stage of surgery, and 4 of them received induced membrane wrapping reconstruction. At the last follow-up, bone defect healing was excellent, the joint function was restored (the rate of excellent and good was 90.5%). The joint range of motion recovered well and the rate of excellent and good was 81.0%.


Induction membrane technique in the treatment of infectious bone defect has advantages of simple operation, rapid healing of bone defects, and low recurrence rate of infection.

The full text of this article is available in PDF format.

Keywords : Induced membrane technique, Masquelet technique, Bone defect, Bone cement, Clinical effect

1  These authors contributed equally.

© 2019  The Authors. Published by Elsevier Masson SAS@@#104157@@
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