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Archives de pédiatrie
Volume 26, n° 3
pages 171-173 (avril 2019)
Doi : 10.1016/j.arcped.2019.02.009
Received : 5 February 2018 ;  accepted : 9 February 2019
Pediatric neurolisteriosis: A diagnosis to consider even in the absence of immunodeficiency
 

L. Picard a, Z. Maakaroun-Vermesse b, C. Hoarau c, P. Castelnau a, d, M. Périvier a, d,
a Service de Neuropédiatrie et handicaps de l’enfant, hôpital pédiatrique Gatien de Clocheville, Centre Hospitalier Régional Universitaire de Tours, 49, boulevard Béranger, 37044 Tours, France 
b Service de médecine interne et de maladies infectieuses, hôpital Bretonneau, Centre Hospitalier Régional Universitaire de Tours, 2, boulevard Tonnellé, 37000 Tours, France 
c Unité transversale d’allergologie et immunologie clinique, hôpital Bretonneau, Centre Hospitalier Régional Universitaire de Tours, 2, boulevard Tonnellé, 37000 Tours, France 
d Inserm, UMR 1253, iBrain, Université de Tours, 37000 Tours, France 

Corresponding author. Service de Neuropédiatrie et handicaps de l’enfant, hôpital pédiatrique Gatien de Clocheville, Centre Hospitalier Régional Universitaire de Tours, 49, boulevard Béranger, 37044 Tours, France.Service de Neuropédiatrie et handicaps de l’enfant, hôpital pédiatrique Gatien de Clocheville, Centre Hospitalier Régional Universitaire de Tours49, boulevard BérangerTours37044France
Abstract

Neurolisteriosis is known to affect vulnerable groups, for example neonates or children with immunodeficiency. This is a key point of the current clinical guidelines regarding pediatric meningitis. We report a rare case of neurolisteriosis in an immunocompetent infant, without the typical signs of listeriosis, which led to a delay in administering the appropriate antibiotherapy. This case illustrates the clinical heterogeneity of neurolisteriosis and the relevance of appropriate polymerase chain reaction (PCR) tests when the clinical presentation differs from the current guidelines. This case also reminds us that raw or unpasteurized milk-based food products pose a risk even in immunocompetent infants or children.

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Keywords : Listeria, Meningitis, Neurolisteriosis, PCR multiplex




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