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Journal Français d'Ophtalmologie
Volume 42, n° 6
pages e229-e237 (juin 2019)
Doi : 10.1016/j.jfo.2019.04.001
Received : 8 Mars 2019 ;  accepted : 18 April 2019
Editor's choice

Interstitial keratitis diagnosis and treatment

A.-S. Gauthier a, , S. Noureddine a, B. Delbosc a, b
a Service d’ophtalmologie, CHU Jean-Minjoz, 2, boulevard Fleming, 25030 Besançon cedex, France 
b Faculté de médecine et de pharmacie, 20, rue Ambroise-Paré, 25000 Besançon, France 

Auteur correspondant.

Interstitial keratitis is a non-ulcerative, non-suppurative, more or less vascularized inflammation of the corneal stroma. The corneal lesions result from the host response to bacterial, viral (40% of cases) or parasitic antigens, or from an autoimmune response (1% of cases) without active corneal infection. The natural history of the disease is divided into two phases: acute and cicatricial. This type of keratitis is less common than ulcerative bacterial keratitis, but it is a non-negligible cause of visual loss. It is associated with systemic or infectious disease and requires early diagnosis and appropriate treatment to optimize visual prognosis and avoid other complications.

The full text of this article is available in PDF format.

Keywords : Interstitial keratitis, Herpes simplex, Syphilis, Cogan

 See this article, unabridged, illustrated and detailed, with electronic enhancements, in EMC-Ophtalmologie: Gauthier AS, Delbosc B. Kératites interstitielles. EMC - Ophtalmologie 2017;15(2):1-14 [Article 21-200-D-15].

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