Premalignant and malignant oral mucosal lesions: Clinical and pathological findings - 21/06/19

Doi : 10.1016/j.jaad.2018.09.060

Mayra B.C. Maymone, DDS, MD, DSc ^a, Robert O. Greer, DDS, ScD ^b,^c,^d,^e,^f, Jeffery Kesecker, DDS ^f, Priya Cherukuri Sahitya, BA ^a, Lauren K. Burdine, BA ^a, Anh-Dao Cheng, BA ^a, Alexandre C. Maymone, DDS ^d, Neelam A. Vashi, MD ^a,^g,^⁎
^a Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts
^b Department of Pathology, Schools of Medicine and Dentistry, University of Colorado, Denver, Colorado
^c Department of Dermatology, Schools of Medicine and Dentistry, University of Colorado, Denver, Colorado
^d Department of Dentistry, Schools of Medicine and Dentistry, University of Colorado, Denver, Colorado
^e Department of Medicine, Schools of Medicine and Dentistry, University of Colorado, Denver, Colorado
^f Department of Dentistry and Oral Surgery, Denver Health Medical Center, Denver, Colorado
^g US Department of Veteran Affairs, Boston Health Care System, Boston, Massachusetts

^∗Correspondence to: Neelam A. Vashi, MD, Boston University School of Medicine, Department of Dermatology, 609 Albany St, J108, Boston, MA 02118.Boston University School of MedicineDepartment of Dermatology609 Albany St, J108BostonMA02118

Abstract

The second article in this continuing medical education series discusses the clinical and histopathologic features of common premalignant and malignant lesions of the oral cavity. It is imperative for dermatologists to be able to appropriately recognize suspicious lesions, determine the need to obtain a biopsy specimen, counsel, and refer patients presenting with premalignant or malignant conditions. Given the higher rates of mortality and morbidity of oral mucosal malignancies because of late diagnosis, appropriate treatment with multidisciplinary care in a timely manner is essential to patients with these neoplasms.

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Key words : adenoid cystic carcinoma, erythroplakia, mucoepidermoid carcinoma, mucosal melanoma, oral leukoplakia, oral lichen planus, oral mucosal squamous cell carcinoma, proliferative verrucous leukoplakia, verrucous carcinoma

Abbreviations used : ACC, MEC, OL, OLP, OMM, OmSCC, OVC, PVL