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Sous presse. Epreuves corrigées par l'auteur. Disponible en ligne depuis le mardi 17 mars 2020
Doi : 10.1016/j.arcped.2020.01.008
Received : 20 December 2018 ;  accepted : 25 January 2020
Smoke inhalation injury in a 2-year-old domestic fire victim

G. Geslain a, , B. Tilea b, F. Heraut c, R. Rubinsztajn a
a Pediatric Intensive Care Unit, Raymond-Poincaré Hospital, AP–HP, 92380 Garches, France 
b Radiology, Robert-Debré Hospital, AP–HP, 75019 Paris, France 
c Physiological Explorations, Raymond-Poincaré Hospital, AP–HP, 92380 Garches, France 

Corresponding author at: Pediatric Intensive Care Unit, Robert-Debré Hospital, AP-HP, 48 boulevard Sérurier 75019 Paris, France.Pediatric Intensive Care Unit, Robert-Debré Hospital, AP-HP48 boulevard Sérurier Paris75019France

Smoke inhalation injury is common in victims of domestic fires, among whom children are the most vulnerable. Cyanide poisoning may occur in addition to carbon monoxide poisoning and is challenging to diagnose. In France, the recommended antidotes are hydroxocobalamin for cyanide and hyperbaric oxygen for carbon monoxide. We managed a 26-month-old girl who sustained smoke inhalation injury with both carbon monoxide and cyanide poisoning during a house fire. Despite hydroxocobalamin and sodium thiosulfate therapy combined with hyperbaric oxygen, she had residual neurological impairments 3 months after the injury. The treatment challenges and detailed neurological follow-up data are described.

The full text of this article is available in PDF format.

Keywords : Smoke inhalation, Domestic fire, Child, Hyperbaric oxygen, Hydroxocobalamin

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