Clinical and functional status in 88 rheumatoid arthritis patients followed for 15 years or more by office-based ( n = 41) or hospital-based ( n = 47) physicians - 01/01/02
Yves Laborie, Jean-Marie Berthelot * , Christophe Alliaume, Jean Baron, Jean-Pierre Caumon, Véronique Desmas, Alain Rossard, Yves Maugars, Alain Prost*Correspondence and reprints: service de rhumatologie, Hôtel-Dieu, CHU Nantes, 44093, Nantes cedex, France
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Résumé |
Objective. To determine the very long-term clinical and functional outcomes in rheumatoid arthritis (RA) patients followed by office-based or hospital-based physicians. Patients and methods. A questionnaire including items on clinical outcomes (active disease, remission, burn-out) and the Health Assessment Questionnaire (HAQ) was mailed to 122 patients with RA of at least 15 years'duration; 61 were followed by office-based physicians and 61 by hospital-based physicians. In the 88 (72%) respondents, mean age was 63±13 years and mean disease duration was 20.1±8.7 years. Results. None of the patients experienced burn-out of their disease, and only six (7%) met Pinals'remission criteria. However, 23 (26%) reported a current subjective remission with a mean duration of 8.5±5.9 months. Although the mean pain score in the 88 patients was 4.1±2.3, only 50 (56%) patients reported a physician visit during the last 6 months. HAQ scores varied widely, the mean being 1.11±0.84. Forty (46%) patients had a history of arthroplasty (knee or hip in 29 (33%)). Of the 34 nonrespondents, seven had died (at a mean age of 74 years), and in four of these seven the cause of death was infection or immobility-related complications; in the 27 survivors, disease activity was considered minimal by the physicians or patients, 11 (41%) patients believed they were in remission, and mean time since the last physician visit was 3.9 years. Conclusion. Although burn-out within 20 years of RA onset seems exceedingly rare, clinical activity is milder than in early RA; over one-fourth of our patients believed they were in remission and over one half had not seen a physician during the last 6 months. Functional outcomes varied widely across patients but were acceptable overall, a result that is partly ascribable to the favorable effects of surgery. No differences in functional outcomes were found between patients followed by office-based physicians and those followed by hospital-based physicians.
Mots clés : arthroplasty ; HAQ ; long-term outcome ; remission ; rheumatoid arthritis.
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Vol 69 - N° 2
P. 181-188 - mars 2002 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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