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Annales de Dermatologie et de Vénéréologie
Vol 127, N° 4  - mai 2000
p. 389
Doi : AD-05-2000-127-4-0151-9638-101019-ART92
Cas clinique

Dermatomyosite et cancer du cavum : 3 observations
 

H. Boussen [1], A. Mebazaa [1], S. Gritli [1], S. Khalfallah [1], S. Touati [1], A. El May [1], F. Benna [1], F. Ben Ayed [1], R. Nouira [2], N. Bouaouina [2], A. Ladgham [1]
[1] Service de Carcinologie Médicale, Institut Salah Azaïz, boulevard du 9-Avril, Bab Saadoun, Tunis, Tunisie.
[2] Hôpital Farhat Hached, Sousse, Tunisie.

Abstract
Introduction

Le cancer du nasopharynx est une affection relativement fréquente en Tunisie avec une incidence évaluée à 1,8/100 000. Cette tumeur particulièrement évolutive est fréquemment associée à des syndromes paranéoplasiques.

Observations

Nous avons observé 3 cas de dermatomyosite associés à des carcinomes indifférenciés du nasopharynx chez des malades âgés respectivement de 40, 24 et 65 ans. Dans les 3 cas, l'évolution du syndrome paranéoplasique a été parallèle de celle de la tumeur.

Discussion

La dermatomyosite est un des syndromes paranéoplasiques associés au cancer du nasopharynx. Toute dermatomyosite devrait motiver en Tunisie un examen systématique du cavum.

Abstract
Dermatomyositis and nasopharyngeal carcinoma: 3 cases.
Background

Nasopharyngeal carcinoma is a common cancer in Tunisia with an estimated incidence of 1.8/100,000. The tumor shows a characteristic association with paraneoplastic syndromes.

Case reports

We report three cases of histologically proven dermatomyositis associated with nasopharyngeal carcinoma in patients aged 40, 24 and 65 years. In all cases, the course of the paraneoplastic syndrome ran parallel to the nasopharyngeal carcinoma.

Discussion

Dermatomyositis is one of the numerous paraneoplastic syndromes associated with nasopharyngeal carcinoma. Systematic examination of the nasopharynx is required in case of dermatomyositis.






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