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Annales de Dermatologie et de Vénéréologie
Vol 130, N° 6-7  - juin 2003
pp. 607-610
Doi : AD-06-2003-130-6-0151-9638-101019-ART3
Alopécie fibrosante frontale post ménopausique : 20 cas
 

V. Vaisse [1], B. Matard [2], P. Assouly [2], C. Jouannique [2], P. Reygagne [2]
[1]  Unité de Dermatologie, Hôpital Tenon, 4, rue de la Chine, 75020 Paris
[2]  Centre de Santé Sabouraud, 2, place du docteur Alfred Fournier, 75010 Paris.

Tirés à part : V. VAISSE [2]

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Introduction

L'alopécie fibrosante frontale post ménopausique est une alopécie cicatricielle décrite récemment par Kossard en 1994 et peu rapportée dans la littérature.

Observations

Il s'agissait d'une étude clinique et histologique rétrospective portant sur une série de 20 observations d'alopécie fibrosante frontale post ménopausique. Les résultats en accord avec les données de la littérature mettent en évidence le caractère stéréotypé de cette entité.

Discussion

L'ensemble des données cliniques et histologiques fait considérer l'alopécie fibrosante frontale post ménopausique comme une forme clinique de lichen plan pilaire touchant la femme âgée. Comme pour le lichen plan pilaire la physiopathologie est inconnue. Cependant, par analogie à d'autres dermatoses lichéniennes, une réaction auto-immune à médiation lymphocytaire T semble jouer un rôle primordial dans sa genèse.

Abstract
Postmenopausal frontal fibrosing alopecia: 20 cases.
Introduction

Postmenopausal frontal fibrosing alopecia is a scarring alopecia that has been recently described by Kossard in 1994 and rarely reported in the literature.

Observations

We have conducted a retrospective clinical and histological study of a series of 20 cases of postmenopausal frontal fibrosing alopecia. The results, in agreement with those inthe literature, revealed the stereotyped nature of this entity.

Discussion

All the clinical and histological data suggest that postmenopausal frontal fibrosing alopecia is a clinical form of lichen planopilaris occurring in elderly women. As with lichen planopilaris its physiopathology is unknown. However, in analogy with other lichen-like dermatoses, a lymphocyte T-mediated autoimmune reaction appears to play a predominant part in its genesis.






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