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Archives de pédiatrie
Volume 8, n° S4
pages 721-725 (septembre 2001)
Doi : S0929-693X(01)80187-1
Infections bactériennes graves du nouveau-né
Severe neonatal infection
 

C. Saizou a, C. Farnoux b, M. Rajguru b, E. Bingen c, Y. Aujard , b
a Service de réanimation, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France 
b service de néonatologie-bactériologie, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France 
c service de microbiologie, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France 

Correspondance.
Résumé

Les infections néonatales primitives et secondaires sont des pathologies fréquentes dont le pronostic des formes septicémiques reste sévère. L'évaluation de la gravité de ces infections est difficile du fait de la non spécificité des signes cliniques et la mortalité semble donc être un bon moyen d'évaluation. Une enquête a été réalisée en France sur le taux de mortalité par infection dans les services de réanimation et de néonatologie durant le 3e trimestre 2000. Dans les 18 services qui ont répondu, le taux de décès est de 9,3 % des admissions (11 infections primitives et 17 infections secondaires). Les décès par infections maternofœtales sont essentiellement dus au streptocoque B et l'E. coli avec un risque plus important chez les grands prématurés.

Les infections secondaires graves ne surviennent que chez les prématurés. Le pronostic dépend avant tout du germe en cause. Ainsi l'évolution des infections à staphylocoque coagulase négatif, les plus fréquentes, est en règle favorable alors que la mortalité des infections à entérobactéries est proche de 40 % et celle des Pseudomonas de 62 %.

The full text of this article is available in PDF format.
Abstract

The prognosis of septicemic forms of early and late neonatal sepsis is severe with a high rate of mortality especially in premature infants. The evaluation of severity is difficult because of the non specificity of the clinical signs and mortality seems to be a good means of evaluation. A study was conducted in France on the mortality due to infection in neonatal intensive care units and neonatology wards during the third trimester 2000. Among 18 units, the mortality rate was 9,3% of admissions, corresponding to 11 early onset sepsis and 17 nosocomial infections. Death in primitive infections is essentially due to group B streptococci and E. coli with a more important risk in low gestationnal age infants. The nosocomial infections arise almost only in premature infant. Prognosis of infections due to Staphylococcus coagulase negative staphylococci, most frequent pathogens is good but mortalitys rate is higher for enterobacteriacae — 40% and for Pseudomonas , 62%.

The full text of this article is available in PDF format.

Mots-clé : infection néonatale / pronostic / mortalité

Keywords : neonatal infection / prognosis / mortality




© 2001  Published by Elsevier Masson SAS.
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