Inverse correlation of each functional status scale of the SF-36 with degree of disease activity in systemic lupus erythematosus (m-SLAM) - 01/01/03
Jihan Saba, Robert J. Quinet * , William E. Davis, Marie Krousel-Wood, Richard Chambers, Natalie Gomez, Leonard Serebro, Priya Nair*Corresponding author. Address: Ochsner Clinic Foundation, Department of Internal Medicine, Section on Rheumatology, 1514 Jefferson Highway, New Orleans, LA 70121, USA.
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Résumé |
Objectives. - To compare systemic lupus erythematosus (SLE) disease activity measured by a modified Systemic Lupus Activity Measure (m-SLAM) with functional/health status measured by the SF-36 questionnaire.
Patients and methods. - m-SLAM and SF-36 scores were obtained on 71 SLE patients during 242 clinic visits over 15 months. Patients were stratified into disease activity groups (m-SLAM <2 = remission; 2-4 = mild; 4-6 = moderate; >6 = severe). Mean SF-36 group scores were compared by analysis of variance (ANOVA).
Results. - Two hundred and nineteen m-SLAM and SF-36 scores were completed. The disease activity groups correlated inversely with the SF-36 scores in all eight subscales, i.e. the patients' perceived health, as assessed by the SF-36, correlated with their disease activity level as measured by the m-SLAM. Inverse correlation of SLAM activity groups with all eight SF-36 subscales was highly statistically significant.
Conclusion. - The significant inverse correlation of the m-SLAM with all domains of the SF-36 in this study provides potentially useful information for evaluating patients with SLE.
Mots clés : SLE (systemic lupus erythematosis) ; SF 36 ; SLAM.
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Vol 70 - N° 5
P. 348-351 - septembre 2003 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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