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Archives de pédiatrie
Volume 16, n° 7
pages 1016-1020 (juillet 2009)
Doi : 10.1016/j.arcped.2009.02.022
Received : 29 January 2008 ;  accepted : 10 February 2009
Rechute extramédullaire annexielle isolée d’une leucémie aiguë lymphoblastique : à propos d’un cas
Isolated extramedullary adnexal relapse of acute lymphoblastic leukemia: A case report
 

H. Bellaaj 1, , A. Moussa 2, N. Gouiaa 3, K. Maazoun 2, I. Frikha 1, M. Medhaffar 1, S. hdiji 1, M. Elloumi 1, T. Souissi 1
1 Service d’hématologie du CHU Hedi chaker de Sfax, Tunisie 
2 CHU Fattouma-Bourguiba, Mounastir, Tunisie 
3 CHU Habib-Bourguiba, Sfax, Tunisie 

Auteur correspondant.
Résumé

La survenue d’une rechute ovarienne isolée d’une leucémie aiguë lymphoblastique (LAL), en rémission complète après une chimiothérapie est une situation rarement décrite. Nous rapportons le cas d’une jeune fille de 12 ans, traitée pour une LAL qui a présenté 4 ans après la fin du traitement initial une rechute ovarienne et tubaire gauche, isolée, tardive sans rechute hématologique ni médullaire, révélée par une masse pelvienne isolée. Le diagnostic a été établi par une biopsie guidée par tomodensitométrie, et une 2e rémission complète a été obtenue après chimiothérapie et chirurgie complémentaire.

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Summary

The occurrence of an isolated ovarian or pelvic relapse of acute lymphoblastic leukemia (ALL) in complete remission after chemotherapy has rarely been described. We report the case of a 12-year-old girl, treated for ALL, who developed an isolated left ovarian and fallopian tube localization without medullary or blood relapse 4 years after the end of the initial treatment. She presented with an isolated pelvic mass. The diagnosis was established by a CT-guided biopsy. The treatment consisted of a second course of chemotherapy and complementary surgery; a second complete remission was obtained.

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Mots clés : Leucémie aiguë lymphoblastique, Rechute extramédullaire, Ovaire




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