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Annales de Dermatologie et de Vénéréologie
Volume 136, n° S4
pages 92-103 (mai 2009)
Doi : 10.1016/S0151-9638(09)74535-1
La toxine peut-elle prévenir le vieillissement ?
Can the botulinum toxin prevent the aging?

C. Le Louarn
59, rue Spontini, 75116 Paris 


Le tonus de repos des muscles de la mimique est démontré dans cette étude comme augmentant progressivement avec le temps. Selon le concept du Face Recurve®, ceci entraîne un transfert graisseux à cause du raccourcissement musculaire.

La toxine botulique est proposée dans une nouvelle utilisation : la diminution du tonus de repos, pour agir sur le vieillissement structurel avant que celui-ci ne devienne visible au repos. Le raccourcissement musculaire est ralenti dans son apparition.

La précision des injections est possible grâce à la détermination de l’emplacement des plaques motrices pour chaque muscle.

Deux autres utilisations classiques, le blocage de la force de contraction maximale et l’effet dermique peuvent s’associer à la diminution du tonus de repos pour les cas plus évolués.

Enfin, la toxine botulique, dans une nouvelle indication, bloque la régénération musculaire après section des faisceaux marqueurs de l’âge et stabilise donc l’effet désiré. Cette nouvelle indication a aussi une application en reconstruction pour agir sur le côté sain hyperactif dans le cadre des paralysies faciales.

The full text of this article is available in PDF format.

This study wants to prouve that the resting tone is increasing with age. On the behalf of the Face Recurve® concept, the deep fat is expelled superficially because of mimic muscle shortening. Botulinum toxin is proposed for a new indication: resting tone decrease in order to slow down muscle shortening and consequently structural aging. Injections can be performed very early in the ageing process, before the appearance at rest of wrinkle, only when it becomes visible in contraction.

Precision of the injection is related to the recent determination of motor end plate location in every mimic muscle.

Two classical uses, the maximum strength of contraction and the dermal injection, are associated to the action on the resting tone for more evolved cases.

Finally, a new possibility for botulinum toxin injection is the blockage of muscular regeneration to stabilize the section of the age marker fascicules performed in the Face Recurve® concept. This new indication is also useful in reconstructive surgery for treatment of the marginal mandibular lip deformity in patients with chronic unilateral facial palsies.

The full text of this article is available in PDF format.

Mots clés : Toxine botulique, Tonus de repos, Régénération musculaire, Face Recurve®

Keywords : Botulinum toxin, Resting tone, Muscular regeneration, Face Recurve®

© 2009  Elsevier Masson SAS. All Rights Reserved.
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