Outcome of group B streptococcal prosthetic hip infections compared to that of other bacterial infections - 21/10/09
, Marina Lavigne b, David Biau d, Philippe Leclerc a, Jean Marc Ziza b, Patrick Mamoudy a, Nicole Desplaces a, c
Corresponding author. Service de Chirurgie Osseuse et Traumatologique, Groupe Hospitalier Diaconesses-Croix Saint-Simon, 125, rue d’Avron, 75020 Paris, France. Tel.: +33 1 4464 1694; fax: +33 1 4464 3337.Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
| pages | 6 |
| Iconographies | 2 |
| Vidéos | 0 |
| Autres | 0 |
Abstract |
Background |
Outcome of streptococcal prosthetic hip infection is often thought to be better than that caused by other pathogens. That supposition was not confirmed in our experience with group B streptococcal prosthetic joint infection.
Objective |
We compared outcomes of group B streptococcal and other-pathogen prosthetic hip infections.
Methods |
One hundred and thirty nine patients, 24 with group B streptococcal and 115 other-pathogen prosthetic hip infections, were included. The primary outcome was the time from surgical treatment to treatment failure, defined as relapse, infection- or treatment-related death. Secondary outcomes were the times from surgical treatment to relapse or any event (event-free survival). The cumulative incidence estimator was used to model primary and secondary outcomes. Multivariable regression analysis was used to determine a set of independent predictors of treatment failure.
Results |
With a median follow-up of 22months, treatment failed more frequently in patients with group B streptococcal prosthetic hip infections (hazard ratio, 4.88 [95% CI, 1.4–17], P=.012). Multivariable analysis retained the American Society of Anesthesiologist score and group B streptococcal infection as independent risk factors of treatment failure; event-free survival was lower for these patients (hazard ratio, 2.64 [95% CI, 1.2–6], P=.02).
Conclusion |
Despite high antibiotic susceptibility, outcomes of group B streptococcal and other-pathogen prosthetic hip infection differ.
Le texte complet de cet article est disponible en PDF.Keywords : Group B streptococcus, Prosthetic hip infection, Outcome
Plan
Vol 76 - N° 5
P. 491-496 - octobre 2009 Retour au numéro
Article précédent
- Growing pains in children: Epidemiological analysis in a Mediterranean population
- Angelos Kaspiris, Chrisi Zafiropoulou
- Low and stable prevalence of rheumatoid arthritis in northern France
- Emmanuel Biver, Véronique Beague, David Verloop, Dominique Mollet, Dominique Lajugie, Guy Baudens, Patrick Neirinck, René Marc Flipo
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’achat d’article à l’unité est indisponible à l’heure actuelle.
Déjà abonné à cette revue ?