Antisynthetases syndrome associated with right heart failure - 09/12/09
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Abstract |
Cardiac involvement is a complication of end stage polymyositis with left heart insufficiency reported to be the most frequent manifestation. We here describe an unusual clinical presentation of antisynthetases syndrome, beginning with right-sided cardiomyopathy associated with right heart failure. A 26 year-old Caucasian male experienced a 6-month clinical course of polyarthritis, fever, sweats, and myalgia. Laboratory studies showed elevated C reactive protein, elevated sedimentation rate, and myolysis associated with anti SSA and anti JO1 antibodies. Electromyography showed a myopathic pattern. Muscle biopsy confirmed the diagnosis of polymyositis. Chest X ray, chest scan, and cardiac echography were normal. One week after hospital admission, the patient developed acute right heart insufficiency, and magnetic resonance imaging showed a right ventricular myocarditis with myocardial inflammatory thickening. Treatment with corticosteroids rapidly improved both symptoms and biological abnormalities.
Le texte complet de cet article est disponible en PDF.Keywords : Polymyositis, Antisynthetases syndrome, Anti JO1 antibody, Right heart failure, Myocarditis
Plan
Vol 76 - N° 6
P. 715-717 - décembre 2009 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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