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Archives of cardiovascular diseases
Volume 103, n° 1
pages 46-52 (janvier 2010)
Doi : 10.1016/j.acvd.2009.06.009
Received : 5 May 2009 ;  accepted : 30 June 2009
Heart involvement in systemic sclerosis: Evolving concept and diagnostic methodologies
Atteinte cardiaque au cours de la sclérodermie systémique : physiopathologie et méthodes diagnostiques

Figure 1

Figure 1 : 

Heart histological analyses. SSc patient with end-stage heart failure requiring heart transplantation; acknowledgments to Pr Jean-Baptiste Michel Inserm U698, CHU Bichat, Paris, France.

Figure 2

Figure 2 : 

Cardiac magnetic resonance imaging. Left ventricular short-axis acquisition immediately after the injection of gadolinium (a: first-pass myocardial perfusion) and 10min after injection (b: delayed enhancement). Early subendocardial hypoenhancement of the left ventricular lateral wall shown on first-pass perfusion is related to impaired microcirculation (coronary computed tomography angiography was normal). Delayed enhancement exhibits linear subendocardial hyperenhancement in the lateral wall and focal intramyocardial hyperenhancement in the septal wall, highly suggestive of myocardial fibrosis.

Figure 3

Figure 3 : 

Cardiac magnetic resonance imaging. Left ventricular short-axis acquisition immediately after the injection of gadolinium. Early hyperenhancement of the left ventricular inferior wall related to myocardial inflammation.

Figure 4

Figure 4 : 

Receiver operating characteristic (ROC) curve for the detection of overall cardiac involvement by N-terminal prohormone brain natriuretic peptide.

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