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Revue du rhumatisme
Volume 71, n° 5
pages 412-414 (mai 2004)
Doi : 10.1016/S1169-8330(03)00327-2
Received : 6 January 2003 ;  accepted : 20 Mars 2003
Méningite aseptique médicamenteuse induite par le léflunomide
Leflunomide-induced aseptic meningitis

Jean David  Cohen * ,  Christian  Jorgensen,  Jacques  Sany
Service d'immunorhumatologie, hôpital Lapeyronie, 34295 Montpellier cedex 5, France 

*Auteur correspondant.

Les méningites aseptiques induites par les médicaments constituent un événement rare, rencontré principalement chez le sujet ayant une maladie auto-immune. Nous rapportons la première observation de méningite aseptique induite par le léflunomide chez un patient atteint de polyarthrite rhumatoïde.

Mots clés  : Méningite aseptique ; Léflunomide ; Polyarthrite rhumatoïde.


Drug-induced aseptic meningitis is uncommon and occurs primarily in patients with autoimmune disease. We report the first known case of leflunomide-induced aseptic meningitis, in a patient with rheumatoid arthritis.

Mots clés  : Aseptic meningitis ; Leflunomide ; Rheumatoid arthritis.

1  Pour citer cet article, utiliser ce titre en anglais et sa référence dans le même volume de Joint Bone Spine.

© 2003  Elsevier SAS. All Rights Reserved.

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