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Comptes Rendus Chimie
Volume 7, n° 10-11
pages 981-988 (octobre 2004)
Doi : 10.1016/j.crci.2003.12.022
Received : 4 August 2003 ;  accepted : 21 December 2003
Annomuricatin C, a novel cyclohexapeptide from the seeds of Annona muricata
 

Alassane Wélé, Yanjun Zhang, Christelle Caux, Jean-Paul Brouard, Jean-Louis Pousset, Bernard Bodo
Laboratoire de chimie des substances naturelles, ESA 8041 CNRS, Muséum national d'histoire naturelle, 63, rue Buffon, 75005 Paris, France 

*Corresponding author.
Abstract

A new cyclohexapeptide, annomuricatin C, cyclo (Pro1–Gly2–Phe3–Val4–Ser5–Ala6–) (1) has been isolated from the methanol extract of the seeds of Annona muricata . The structure was elucidated on the basis of the MS/MS fragmentation using a Q-TOF mass spectrometer equipped with an ESI source, chemical degradation and extensive 2D-NMR. To cite this article: A. Wélé et al., C. R. Chimie 7 (2004) .

The full text of this article is available in PDF format.
Résumé

L'annomuricatine C, un nouveau cyclohexapeptide isolé des graines d'Annona muricata . Un nouveau cyclohexapeptide, l'annomuricatine C, cyclo (Pro1–Gly2–Phe3–Val4–Ser5–Ala6–) a été isolé de l'extrait méthanolique des graines d'Annona muricata . La structure a été déterminée en se basant sur la fragmentation MS/MS en utilisant un spectromètre Q-TOF équipé d'une source d'ionisation par électronébulisation (ESI), la dégradation chimique et la RMN-2D hétéronucléaire. Pour citer cet article : A. Wélé et al., C. R. Chimie 7 (2004) .

The full text of this article is available in PDF format.

Keywords : Cyclic peptide, Annona muricata , Annomuricatin C

Mots clés : Peptide cyclique, Annona muricata , Annomuricatine C




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