Article

3 Iconography
Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text
Service d'aide à la décision clinique
Advertising


Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates

  • You can purchase this item in Pay Per ViewPay per View - FAQ : 30,00 € Taxes included to order
    Pages Iconography Videos Other
    5 3 0 0


Annales de Dermatologie et de Vénéréologie
Volume 137, n° 12
pages 789-793 (décembre 2010)
Doi : 10.1016/j.annder.2010.08.003
Received : 29 June 2009 ;  accepted : 2 August 2010
Fibromyxome acral superficiel : trois observations
Superficial acral fibromyxoma: Three cases
 

O. Cogrel a, , S. Stanislas b, J.-M. Coindre c, P. Guillot a, M. Beylot-Barry a, M.-S. Doutre a, B. Vergier b
a Service de dermatologie, hôpital Haut-Lévêque, CHU de Bordeaux, avenue de Magellan, 33604 Pessac cedex, France 
b Service d’anatomie pathologique, hôpital Haut-Lévêque, CHU de Bordeaux, avenue de Magellan, 33604 Pessac cedex, France 
c Service d’anatomie pathologique, institut Bergonié, 229, cours de l’Argonne, 33076 Bordeaux cedex, France 

Auteur correspondant.
Résumé
Introduction

Nous rapportons trois nouveaux cas de fibromyxome acral superficiel (FAS) et discutons, d’une part, des caractéristiques anatomocliniques qui définissent cette tumeur fibreuse acrale peu fréquente et, d’autre part, des diagnostics différentiels à évoquer devant un aspect de nodule ferme touchant les extrémités.

Observations

Les trois lésions présentaient l’aspect clinique habituel d’un volumineux nodule solitaire de couleur chair déformant l’appareil unguéal d’un orteil ou d’un doigt. Les biopsies montraient, sur un fond fibromyxoïde, une prolifération de cellules fusiformes sans atypies exprimant CD 34 de manière diffuse et, de manière focale et plus inconstante, l’epithelial membrane antigen (EMA) et le CD 99. La recherche par FISH d’une translocation t(17 ; 22) est restée négative dans nos observations.

Discussion

Cette tumeur fibreuse acrale non exceptionnelle est méconnue. Elle peut parfois faire discuter histologiquement un dermatofibrosarcome myxoïde, au pronostic radicalement différent.

The full text of this article is available in PDF format.
Summary
Background

In this report of three new cases of superficial acral fibromyxoma (SAF), we discuss the clinicopathological features of this acral fibrous tumour as well as the differential diagnoses for hard nodules affecting the extremities.

Patients and methods

These three lesions involved the standard presentation of a large solitary flesh coloured nodule causing deformation of a toenail or a fingernail. Biopsy showed the presence within a fibromyxoid tumour of proliferating fusiform cells having no atypical features and expressing CD 34 diffusely, and in more focal and less consistent fashion, epithelial membrane antigen (EMA) and CD 99. FISH testing for translocation t(17; 22) proved negative.

Discussion

This fairly common acral fibrous tumour is poorly known and in certain cases histology results may suggest myxoid dermatofibrosarcoma, which carries a completely different prognosis.

The full text of this article is available in PDF format.

Mots clés : Fibromyxome acral superficiel, Ongle

Keywords : Superficial acral fibromyxoma, Nail




© 2010  Elsevier Masson SAS. All Rights Reserved.
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Close
Article Outline