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Archives of cardiovascular diseases
Volume 104, n° 3
pages 147-154 (mars 2011)
Doi : 10.1016/j.acvd.2010.12.004
Received : 10 September 2010 ;  accepted : 17 December 2010
Spatial distribution of neo-intimal hyperplasia 6 months after zotarolimus-eluting stent implantation, analysed by optical coherence tomography
Distribution spatiale de l’hyperplasie néo-intimale six mois après implantation de stents actifs au zotarolimus analysée par tomographie par cohérence optique
 

Figure 1




Figure 1 : 

Stent analysis on optical coherence tomography millimetric images: (a) qualitative strut analysis (A. covered; B. non-covered; C. malapposed; D. facing collateral); (b) quantitative analysis (neointimal hyperplasia area [green]; lumen area [red]; coverage thickness per strut [red arrows]); (c) longitudinal analysis in five segments of equal length (P2: proximal; P1: proximal-medial; M: medial; D1: distal-medial; D2: distal).


Figure 2




Figure 2 : 

Relationship between strut coverage thickness (μm), neointimal hyperplasia (NIH) obstruction (%) and non-covered strut ratio, studied on 745 optical coherence tomography slices (699 slices with all struts covered; 28 slices with non-covered strut [NCS] ratio<0.15; 12 slices with NCS ratio between 0.15 and 0.30; six slices with NCS ratio>0.30).


Figure 3




Figure 3 : 

Spatial distribution of neointimal hyperplasia (NIH) and strut coverage, 6 months after zotarolimus-eluting stent implantation (n =42), from quantitative optical coherence tomography analysis. A. Mean stent area, NIH area (NIHA) and lumen area (LA) (mm2) in all 745 slices; mean areas in five longitudinal stent segments (P2: proximal; P1: proximal-medial; M: medial; D1: distal-medial; D2: distal). B. Mean strut coverage thickness (μm) in all cross sections and in five longitudinal stent segments (bars), and neointimal hyperplasia (NIH) percentage obstruction (points). C. Mean non-covered strut ratio in all cross sections and in five longitudinal stent segments.


Figure 4




Figure 4 : 

Relationship between mean strut coverage thickness, neointimal hyperplasia (NIH) obstruction measured by optical coherence tomography and stent length (A, B) and stent diameter (C, D), 6 months after zotarolimus-eluting stent implantation (n =42).

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