Skin spicules: A newly described paraneoplastic phenomenon associated with a marginal zone B-cell lymphoma - 07/08/11
Doi : 10.1016/j.jaad.2008.11.016
Stephanie Hu, BS a, Scott R. Granter, MD b, Harley A. Haynes, MD c, Danielle M. Miller, MD, PhD c, ⁎ 
a Harvard Medical School, Brigham and Women’s Hospital, Boston, Massachusetts
b Department of Pathology, Brigham and Women’s Hospital, Boston, Massachusetts
c Department of Dermatology, Brigham and Women’s Hospital, Boston, Massachusetts
Reprint requests: Danielle M. Miller, MD, PhD, Department of Dermatology, Brigham and Women’s Hospital, Harvard Medical School, 221 Longwood Ave, Boston, MA 02115.Abstract |
Paraneoplastic signs are an important clue to diagnosing an associated malignancy. We report an unusual variant of the sign of Leser-Trélat in a patient with a low-grade B-cell lymphoproliferative disorder and intertriginous skin spicules with histologic morphology of minute seborrheic keratoses.
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| Funding sources: None. |
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| Conflicts of interest: None declared. |
© 2008
American Academy of Dermatology, Inc.. Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 60 - N° 5
P. 852-855 - mai 2009 Retour au numéro
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